9Z20

Cryo-EM structure of human TRPM4 channel in complex with EGTA and TPPO at 37 degrees Celsius (consensus)

Summary for 9Z20

Entry DOI	10.2210/pdb9z20/pdb
EMDB information	73758
Descriptor	Transient receptor potential cation channel subfamily M member 4 (1 entity in total)
Functional Keywords	ion channel, trp channel, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	537825.94
Authors	Jinhong, H.,Wei, L.,Juan, D. (deposition date: 2025-11-04, release date: 2026-06-10)
Primary citation	Jinhong, H.,Sofia, I.,Sung Jin, P.,Junuk, L.,Jennifer, C.,Garrett, O.,Jiangnan, S.,Juan, D.,Wei, L. Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.51 Å)

Structure validation