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9Z1Z

Cryo-EM structure of human TRPM4 channel in complex with calcium and TPPO at 18 degrees Celsius (consensus)

This is a non-PDB format compatible entry.
Summary for 9Z1Z
Entry DOI10.2210/pdb9z1z/pdb
EMDB information73757
DescriptorTransient receptor potential cation channel subfamily M member 4, CALCIUM ION, oxotri(phenyl)-lambda~5~-phosphane (3 entities in total)
Functional Keywordsion channel, trp channel, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total formula weight539099.39
Authors
Hu, J.,Lu, W.,Du, J. (deposition date: 2025-11-04, release date: 2026-06-10)
Primary citationJinhong, H.,Sofia, I.,Sung Jin, P.,Junuk, L.,Jennifer, C.,Garrett, O.,Jiangnan, S.,Juan, D.,Wei, L.
Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.63 Å)
Structure validation

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