9YYG

AI-generated RNA-guided nuclease TAM-bound state

Summary for 9YYG

• Entry DOI: 10.2210/pdb9yyg/pdb
• EMDB information: 73644
• Descriptor: AI-designed RNA-guided nuclease, RNA (116-MER), DNA (5'-D(*GP*GP*TP*TP*GP*AP*TP*C)-3'), ... (4 entities in total)
• Functional Keywords: crispr, nuclease, ai, evolution scale modeling, inverse folding, esm-if1, tnpb, tam, pam, spacer, exonuclease, dna binding protein-dna complex, enzyme, ribonucleoprotein, rna, rna-guided nuclease, cas12, isdra2, esm, rna binding protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 94403.49

Authors

Skopintsev, P.,Esain-Garcia, I.,Doudna, J. (deposition date: 2025-10-29, release date: 2026-07-15)

• Primary citation: Skopintsev, P.,Esain-Garcia, I.,Doudna, J.; AI-generated RNA-guided nuclease TAM-bound state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)