9YXV

Cryo-EM structure of the core region of cIL-U1A-Fab1R-PGA1-sfFab quaternary complex at 2.9 A resolution

Summary for 9YXV

• Entry DOI: 10.2210/pdb9yxv/pdb
• EMDB information: 73618
• Descriptor: U1 small nuclear ribonucleoprotein A, Hairpin II of the U1 snRNA (U1hpII), Protein G, ... (8 entities in total)
• Functional Keywords: antibody, fab, rna, ribozyme, u1a, ribonucleoprotein (snrnp) complex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 127872.52

Authors

Filippova, E.V.,Kossiakoff, A.A. (deposition date: 2025-10-27, release date: 2026-05-27)

• Primary citation: Filippova, E.V.,Krochmal, D.,Mukherjee, S.,Piccirilli, J.A.,Kossiakoff, A.A.; A universal Fab targeting a conserved U1A-RNA epitope for RNA structure determination by cryo-EM; Nucleic Acids Res., 54:-, 2026; DOI: 10.1093/nar/gkag502

Experimental method

ELECTRON MICROSCOPY (2.9 Å)