9YVH

Cryo-EM structure of BA.5 spike, Closed conformation

Summary for 9YVH

• Entry DOI: 10.2210/pdb9yvh/pdb
• EMDB information: 73524
• Descriptor: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: sars-cov-2, entry, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 3
• Total formula weight: 422112.22

Authors

Ye, G.,Bu, F.,Li, F. (deposition date: 2025-10-23, release date: 2026-08-26)

• Primary citation: Mou, H.,Gao, B.,Ye, G.,Bu, F.,Zhang, L.,Farzan, M.,Li, F.,Choe, H.; A SARS-CoV-2 entry inhibitor trimerizes to lock the spike trimer in its closed conformation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.83 Å)