9YSQ

Structure of a human NUAK1-MARK3 kinase domain chimera in complex with inhibitor

This is a non-PDB format compatible entry.

Summary for 9YSQ

• Entry DOI: 10.2210/pdb9ysq/pdb
• Descriptor: MAP/microtubule affinity-regulating kinase 3, 3-({5-chloro-2-[2-(difluoromethoxy)-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl}amino)thiophene-2-carboxamide (3 entities in total)
• Functional Keywords: hippo pathway, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 76765.51

Authors

Mao, D.Y.L.,Chini, F.D.,Sicheri, F. (deposition date: 2025-10-19, release date: 2026-04-08)

• Primary citation: Mao, D.Y.L.,Chini, F.D.,Sicheri, F.; Structure of a human NUAK1-MARK3 kinase domain chimera in complex with inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)