9YRC

p97Ufd1-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP

Summary for 9YRC

• Entry DOI: 10.2210/pdb9yrc/pdb
• EMDB information: 73365
• Descriptor: Transitional endoplasmic reticulum ATPase, Nuclear protein localization protein 4 homolog, Ubiquitin recognition factor in ER-associated degradation protein 1, ... (6 entities in total)
• Functional Keywords: p97, vcp, aaa+ atpase, translocase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 653269.12

Authors

Li, H.,Rapoport, T. (deposition date: 2025-10-16, release date: 2026-03-25)

• Primary citation: Li, H.,Guan, H.,Rapoport, T.A.; The deubiquitinating enzyme Otu1 releases substrates from the conserved initiation complex of the Cdc48/p97 ATPase for proteasomal degradation.; Sci Rep, 2026; PubMed: 41795027; DOI: 10.1038/s41598-026-42811-6

Experimental method

ELECTRON MICROSCOPY (2.97 Å)