9YMJ

RQd20_wk56_28 Fab in complex with V703-0537_L14 SOSIP and 3BNC117 Fab

Summary for 9YMJ

• Entry DOI: 10.2210/pdb9ymj/pdb
• EMDB information: 73108
• Descriptor: 3BNC117 Fab heavy chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: hiv-1, env, nhp, v3 glycan, bg18, germline targeting, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 15
• Total formula weight: 526356.85

Authors

Phulera, S.,Ozorowski, G.,Ward, A.B. (deposition date: 2025-10-10, release date: 2026-07-08)

• Primary citation: Steichen, J.M.,Madden, P.J.,Flynn, C.T.,Phulera, S.,Shil, M.,Kalyuzhniy, O.,Liguori, A.,Kifude, C.,Sewall, L.M.,Cottrell, C.A.,Ma, K.M.,Baboo, S.,Diedrich, J.K.,McKenney, K.,deCamp, A.C.,Carnathan, D.G.,Phung, I.,Ramezani-Rad, P.,Marina-Zarate, E.,Freeman, B.,Xie, Z.,Lee, J.H.,Sincomb, T.,Phelps, N.,Lu, D.,Goodwin, D.,Tingle, R.,Adachi, Y.,Alavi, N.,Tran, J.,Tran, A.S.,Nascimento, A.,Sovie, C.,Bader, D.L.V.,Voic, H.,Zhou, X.,Pixton, G.,Walsh, A.,Melo, M.B.,Schiffner, T.,Batista, F.D.,Burton, D.R.,Irvine, D.J.,Paulson, J.C.,Yates, J.R.,Ozorowski, G.,Ward, A.B.,Silvestri, G.,Crotty, S.,Schief, W.R.; Vaccination elicits HIV broadly neutralizing antibodies in primates; Nature, 2026; DOI: 10.1038/s41586-026-10837-5

Experimental method

ELECTRON MICROSCOPY (3.4 Å)