9YLM

BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGTCCA (12-mer)

Summary for 9YLM

• Entry DOI: 10.2210/pdb9ylm/pdb
• Descriptor: B-cell lymphoma/leukemia 11A, DNA Strand II, DNA Strand I, ... (6 entities in total)
• Functional Keywords: transcription factor, dna binding, transcription, transcription-dna complex, globin locus, dna binding protein, transcription/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 20734.88

Authors

Horton, J.R.,Cheng, X. (deposition date: 2025-10-08, release date: 2026-03-04)

• Primary citation: Yu, M.,Das, P.,Horton, J.R.,Zhou, J.,Lee, J.,Hong, T.,Lu, Y.,Estecio, M.R.,Iakova, P.A.,Jain, A.K.,Sbardella, G.,Xiong, Y.,Jin, J.,Blumenthal, R.M.,Huang, Y.,Zhang, X.,Cheng, X.; Regulation of BCL11A DNA binding and expression in human erythrocyte precursor HUDEP-2 cells; Biorxiv, 2026; DOI: 10.64898/2026.02.06.704516

Experimental method

X-RAY DIFFRACTION (1.91 Å)