9YE4

Crystal structure of the human DCAF1 WDR domain in complex with OICR-41110

This is a non-PDB format compatible entry.

Summary for 9YE4

• Entry DOI: 10.2210/pdb9ye4/pdb
• Descriptor: DDB1- and CUL4-associated factor 1, (4P)-4-(4-chloro-2-fluorophenyl)-N-[(1S)-1-(3-chloro-4-fluorophenyl)-2-cyanoethyl]-5-[(1E)-3-oxo-3-(piperidin-1-yl)prop-1-en-1-yl]-1H-pyrrole-3-carboxamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: wd-repeat, wdr, dcaf1, sgc, structural genomics, psi-2, protein structure initiative, structural genomics consortium, protein transport
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72424.86

Authors

kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Mamai, A.,Al-awar, R.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2025-09-23, release date: 2025-11-12)

• Primary citation: kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Mamai, A.,Al-awar, R.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC); Crystal structure of the human DCAF1 WDR domain in complex with OICR-41110; To be published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)