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9YCW

Crystal structure of USP16 ZnF-UBP domain

Summary for 9YCW
Entry DOI10.2210/pdb9ycw/pdb
DescriptorUbiquitin carboxyl-terminal hydrolase 16, ZINC ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsusp16, deubiquitinase, dub, protease, ubiquitin, histone, nucleosome, ubiquitin binding domain, protein binding
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total formula weight43870.76
Authors
Alexandrovics, J.A.,Komander, D. (deposition date: 2025-09-19, release date: 2026-05-20)
Primary citationAlexandrovics, J.A.,Agrata, R.,Schenk, P.,Cerra, A.,Nachbur, U.,Babon, J.J.,Komander, D.
The ZnF-UBP domain regulates USP16 activity by dislodging ubiquitin from the active site
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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PDB entries from 2026-05-27

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