9YC2

Crystal structure of USP49 ZnF-UBP domain

Summary for 9YC2

• Entry DOI: 10.2210/pdb9yc2/pdb
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 49, SULFATE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: usp49, deubiquitinase, dub, protease, ubiquitin, histone, nucleosome, ubiquitin binding domain, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 12548.46

Authors

Alexandrovics, J.A.,Komander, D. (deposition date: 2025-09-18, release date: 2025-10-29)

• Primary citation: Alexandrovics, J.A.,Agrata, R.,Schenk, P.,Cerra, A.,Nachbur, U.,Babon, J.J.,Komander, D.; The ZnF-UBP domain regulates USP16 activity by dislodging ubiquitin from the active site; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)