9Y8B

Human p38 ALPHA MAPK:MW164 pyridazine inhibitor complex

This is a non-PDB format compatible entry.

Summary for 9Y8B

• Entry DOI: 10.2210/pdb9y8b/pdb
• Descriptor: Mitogen-activated protein kinase 14, 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, (3P)-6-(1-methylpiperidin-4-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine, ... (4 entities in total)
• Functional Keywords: serine/threonine-protein kinase, protein kinase domain, transferase, atp binding, phosphorylation, cytosol, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42202.18

Authors

Brunzelle, J.S.,Shuvalova, L.,Roy, S.M.,Watterson, D.M. (deposition date: 2025-09-11, release date: 2025-09-24)

• Primary citation: Brunzelle, J.S.,Shuvalova, L.,Roy, S.M.,Watterson, D.M.; Human p38 ALPHA MAPK:MW164 pyridazine inhibitor complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)