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9Y5X

Crystal structure of shorter construct of SHP2 unbound N-SH2 domain

Summary for 9Y5X
Entry DOI10.2210/pdb9y5x/pdb
DescriptorIsoform 1 of Tyrosine-protein phosphatase non-receptor type 11, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... (5 entities in total)
Functional Keywordsshp2, phosphatase, sh2, allostery, protein binding
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight12290.71
Authors
Padua, R.A.P.,Sullivan, C.,Glaser, A.,Ojoawo, A.,Kern, D. (deposition date: 2025-09-05, release date: 2026-01-07)
Primary citationPadua, R.A.P.,Glaser, A.,Ojoawo, A.,Kern, D.
Crystal structure of ligand free N-SH2 domain of SHP2
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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PDB entries from 2026-01-28

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