9Y4P

Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight base pair linker

Summary for 9Y4P

• Entry DOI: 10.2210/pdb9y4p/pdb
• EMDB information: 72487
• Descriptor: Histone H3, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (11 entities in total)
• Functional Keywords: dnmt3a2/dnmt3b3, dna methylation, h3k36me2 di-nucleosome, dna binding protein
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 26
• Total formula weight: 992284.42

Authors

Xie, X.,Zhou, X.E.,Worden, E.J.,Jones, P.A. (deposition date: 2025-09-03, release date: 2026-02-18)

• Primary citation: Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.J.,Jones, P.A.; The structure basis for de novo DNA methylation in chromatin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.84 Å)