9Y3P

Eukaryotic translation initiation factor 2-B in its apo form (active-state)

Summary for 9Y3P

Entry DOI	10.2210/pdb9y3p/pdb
EMDB information	72462
Descriptor	Translation initiation factor eIF2B subunit epsilon, Translation initiation factor eIF2B subunit beta, Translation initiation factor eIF2B subunit delta, ... (9 entities in total)
Functional Keywords	guanine nucleotide exchange factor, gef, translation, initiation
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	425444.28
Authors	Dalwadi, U.,Croll, T.,Subramanian, A.,Lee, D.J.,Arthur, C.,Walter, P.,Frost, A. (deposition date: 2025-09-02, release date: 2026-06-24)
Primary citation	Dalwadi, U.,Subramanian, A. Pharmacological activation and viral suppression of the integrated stress response reveal a disordering switch in eIF2B To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation