9XQB

Cryo-EM structure of the human A2A adenosine receptor in complex with a Fab antibody fragment

Summary for 9XQB

Entry DOI	10.2210/pdb9xqb/pdb
EMDB information	67107
Descriptor	Fab Light chain, A2A receptor-BRIL, Fab Heavy chain (3 entities in total)
Functional Keywords	cryo-em lip-ms, membrane protein
Biological source	Mus musculus More
Total number of polymer chains	3
Total formula weight	77151.03
Authors	Miyashita, Y.,Konno, R.,Ogasawara, S.,Okuda, Y.,Takamuku, Y.,Moriya, T.,Saito, T.,Murata, T.,Ohara, O.,Kawashima, Y. (deposition date: 2025-11-18, release date: 2026-01-07)
Primary citation	Miyashita, Y.,Konno, R.,Ogasawara, S.,Okuda, Y.,Takamuku, Y.,Moriya, T.,Saito, T.,Murata, T.,Ohara, O.,Kawashima, Y. Rapid and Label-Free Structural Proteomics Using One-Step Swift Trypsin LiP-MS. Acs Omega, 2025 Cited by DOI: 10.1021/acsomega.5c11109 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.45 Å)

Structure validation