9XG7

The crystal structure of MERS-CoV Main protease in complex with inhibitor FD2-21

This is a non-PDB format compatible entry.

Summary for 9XG7

• Entry DOI: 10.2210/pdb9xg7/pdb
• Descriptor: 3C-like proteinase nsp5, 7-(5-azanylpyridin-3-yl)-2-(2-chlorophenyl)-5,7-diazaspiro[3.4]octane-6,8-dione (3 entities in total)
• Functional Keywords: mers-cov, main protease, inhibitor, viral protein
• Biological source: Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (MERS-CoV, Betacoronavirus England 1)
• Total number of polymer chains: 4
• Total formula weight: 133407.73

Authors

Zhong, B.S.,Luo, G.,Wang, G.,Lu, W.Y. (deposition date: 2025-10-29, release date: 2026-05-27)

• Primary citation: Zhong, B.S.,Luo, G.,Wang, G.,Lu, W.Y.; The crystal structure of MERS-CoV Main protease in complex with inhibitor FD2-21; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.53 Å)