9XB4

Crystal structure of Mrt4 (L96C) mutant

Summary for 9XB4

• Entry DOI: 10.2210/pdb9xb4/pdb
• Descriptor: Large ribosomal subunit protein uL10 (2 entities in total)
• Functional Keywords: fumaramidmycin-based derivatives, azole-resistant fungi, ribosome assembly factor, target identification, protein-rna interaction, rna binding protein
• Biological source: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
• Total number of polymer chains: 1
• Total formula weight: 31817.77

Authors

Cao, H.,Hu, X.,Li, W.,Chang, M.,Zhang, Y.,Chu, Y.,Ren, Y.,Wan, J. (deposition date: 2025-10-23, release date: 2026-02-04)

• Primary citation: Cao, H.,Hu, X.,Li, W.,Chang, M.,Zhang, Y.,Chu, Y.,Ren, Y.,Wan, J.; Inhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an unexploited antifungal strategy; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)