9XB0

Crystal structure of KRAS-G12D/Y96S mutant in complex with MRTX-1133

Summary for 9XB0

• Entry DOI: 10.2210/pdb9xb0/pdb
• Descriptor: Isoform 2B of GTPase KRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: inhibitor, complex structure, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 22671.30

Authors

Zhang, X.L.,Zhang, X.Y.,Zhang, Y.Z.,Liu, L.,Xu, C.,Bai, F. (deposition date: 2025-10-23, release date: 2026-10-28)

• Primary citation: Zhang, X.L.,Zhang, X.Y.,Zhang, Y.Z.,Liu, L.,Xu, C.,Bai, F.; Crystal structure of KRAS-G12D/Y96S mutant in complex with MRTX-1133; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.23 Å)