9X2K

AARS1 bound with XY353 and Gly-SA

This is a non-PDB format compatible entry.

Summary for 9X2K

• Entry DOI: 10.2210/pdb9x2k/pdb
• Descriptor: Alanine--tRNA ligase, cytoplasmic, 5'-O-(glycylsulfamoyl)adenosine, ~{N}-(5-chloranyl-1,3-thiazol-2-yl)ethanamide, ... (5 entities in total)
• Functional Keywords: inhibitor, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 43880.94

Authors

Huang, Y.,Liu, S.,Min, J. (deposition date: 2025-10-05, release date: 2026-08-05)

• Primary citation: Huang, Y.,Liu, S.,Min, J.; Covalent Allosteric Inhibition of AARS1 Lactyltransferase; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.71 Å)