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9WU2

Crystal structure of cZ22-Fab in complex with left-handed dC(GC)3 DNA

Summary for 9WU2
Entry DOI10.2210/pdb9wu2/pdb
DescriptorcZ22-Fab heavy chain, cZ22-Fab light chain, DNA (5'-D(*CP*GP*CP*GP*CP*GP*C)-3'), ... (5 entities in total)
Functional Keywordsantibody, z-dna, complex, immune system
Biological sourceMus musculus
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Total number of polymer chains18
Total formula weight309042.75
Authors
Lee, C.C.,Hsu, S.F.,Ko, T.P.,Wang, A.H.J. (deposition date: 2025-09-17, release date: 2026-02-18)
Primary citationLee, C.C.,Hsu, S.F.,Chang, Y.W.,Chen, Y.W.,Ho, M.R.,Sugiyama, H.,Wang, A.H.J.
Structural Basis of B-to-Z DNA Transition Driven by an Anti-Z-DNA Antibody
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

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PDB entries from 2026-03-11

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