9WTX

structure of hOCTN1-Ergothioneine complex

Summary for 9WTX

• Entry DOI: 10.2210/pdb9wtx/pdb
• EMDB information: 66226
• Descriptor: Solute carrier family 22 member 4, trimethyl-[(2S)-1-oxidanyl-1-oxidanylidene-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propan-2-yl]azanium (2 entities in total)
• Functional Keywords: transporter, drug target, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 62431.03

Authors

Xu, B.,Wang, Y. (deposition date: 2025-09-17, release date: 2026-09-23)

• Primary citation: Xu, B.,Liang, S.,Wang, Z.,Zhou, X.,Wang, L.,Liang, Q.,Liu, X.,Guo, W.,Shi, S.,Zhu, C.,Ye, S.,Lou, Z.,Wang, Y.; Structural and mechanistic insights into OCTN1-mediated transport and cancer cell proliferation; Nat Commun, 2026; DOI: 10.1038/s41467-026-77727-2

Experimental method

ELECTRON MICROSCOPY (3.37 Å)