9WS2

Crystal structure of nucleotide-bound PAK2 kinase domain containing K278R mutant

Summary for 9WS2

• Entry DOI: 10.2210/pdb9ws2/pdb
• Descriptor: PAK-2p34, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, GUANIDINE, ... (5 entities in total)
• Functional Keywords: kinase fold, active conformation, phosphorylation at thr402, amp-pnp-bound structure, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 35532.91

Authors

Chen, F.Y.,Hu, H.-F.,Wang, J.,Luo, Z.P.,Wu, J.-W.,Wang, Z.-X. (deposition date: 2025-09-12, release date: 2026-09-16)

• Primary citation: Chen, F.Y.,Hu, H.-F.,Wang, J.,Luo, Z.P.,Wu, J.-W.,Wang, Z.-X.; Kinetic and structural insights into the autoactivation of PAK2 kinase domain: A research paradigm for studying self-activating enzyme; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)