9WPM

Cryo-EM structure of the apo-ConsOR5-Gs complex

Summary for 9WPM

• Entry DOI: 10.2210/pdb9wpm/pdb
• EMDB information: 66145
• Descriptor: Consensus OR5 Olfactory receptor, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Nanobody-35, ... (6 entities in total)
• Functional Keywords: or5 family, receptor, membrane protein/immune system, membrane protein-immune system complex
• Biological source: synthetic construct; More
• Total number of polymer chains: 6
• Total formula weight: 167184.44

Authors

Rong, N.K.,Zhang, M.H.,Yang, F.,Sun, J.P. (deposition date: 2025-09-09, release date: 2026-01-28)

• Primary citation: Han, X.,Zhang, M.H.,Rong, N.K.,Zhu, K.K.,Pei, Y.,Ge, X.Y.,Liu, Q.,Lu, H.,Liu, J.,Zhang, L.J.,Bao, H.Q.,Pi, J.H.,Fan, L.,Fu, Y.,Shao, X.H.,Yan, W.Q.,Gao, X.H.,Zhang, M.Y.,Guo, L.L.,Lu, Y.,Ning, S.L.,Zhang, H.,Xu, Y.F.,Feng, X.Y.,Cheng, J.,Xia, M.,Li, Q.,Yu, X.,Yang, F.,Sun, J.P.; Mechanistic insights into fatty acid odor detection mediated by class II olfactory receptors; Cell(Cambridge,Mass.), 2026; DOI: 10.1016/j.cell.2025.12.018

Experimental method

ELECTRON MICROSCOPY (2.6 Å)