9WOP

Cryo-EM structure of ClassIII Lanthipeptide modification enzyme TherKC with chain A bounded to substrate TherA and ATPrS.

Summary for 9WOP

• Entry DOI: 10.2210/pdb9wop/pdb
• EMDB information: 66127
• Descriptor: Lantibiotic, Protein kinase domain-containing protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total)
• Functional Keywords: lanthipeptide modification enzyme, peptide binding protein
• Biological source: Thermoactinomyces sp. DSM 45892; More
• Total number of polymer chains: 2
• Total formula weight: 104563.22

Authors

Zhang, H.,Luo, M. (deposition date: 2025-09-07, release date: 2026-09-02)

• Primary citation: Zhang, H.,Luo, M.; Structural Basis for the lanthipeptide biosynthesis mechanism of a dimeric Class III lanthipeptide synthetase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.25 Å)