9WOA

Crystal structure of SARS-Cov-2 main protease E166V mutant in complex with Telaprevir

Summary for 9WOA

• Entry DOI: 10.2210/pdb9woa/pdb
• Related PRD ID: PRD_002448
• Descriptor: 3C-like proteinase nsp5, (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide (3 entities in total)
• Functional Keywords: e166v, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68272.99

Authors

Li, W.W.,Guo, L. (deposition date: 2025-09-06, release date: 2026-09-09)

• Primary citation: Li, W.W.,Guo, L.,Zhou, X.L.,Zeng, P.,Li, J.; Crystal structure of SARS-Cov-2 main protease E166V mutant in complex with Telaprevir; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.08 Å)