9WNF

5HT2AR-miniGq heterotrimer in complex with a selective agonist IHCH-2330

This is a non-PDB format compatible entry.

Summary for 9WNF

• Entry DOI: 10.2210/pdb9wnf/pdb
• EMDB information: 66116
• Descriptor: 5-hydroxytryptamine receptor 2A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (5 entities in total)
• Functional Keywords: gpcr, serotonin receptor, membrane protein, 5ht2ar
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 140656.22

Authors

Tang, L.,Ji, Y.,Cheng, J.,Wang, S. (deposition date: 2025-09-04, release date: 2026-09-09)

• Primary citation: Tang, L.,Ji, X.,Cao, D.,Li, H.,Wang, S.,Cheng, J.; Mechanistic Basis for 5-HT2AR Over 5-HT2BR Activation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.13 Å)