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9WND

5HT2AR-miniGq heterotrimer in complex with a psychedelic psilocin

Summary for 9WND
Entry DOI10.2210/pdb9wnd/pdb
EMDB information66114
Descriptor5-hydroxytryptamine receptor 2A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (5 entities in total)
Functional Keywordsgpcr, serotonin receptor, membrane protein, 5ht2ar
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight139257.70
Authors
Cao, M.,Li, H.,Cheng, J.,Wang, S.,Tang, L.,Ji, X. (deposition date: 2025-09-04, release date: 2026-09-09)
Primary citationTang, L.,Ji, X.,Cao, D.,Li, H.,Cheng, J.,Wang, S.
Mechanistic Basis for 5-HT2AR Over 5-HT2BR Activation
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation
No wwPDB Validation report is currently available for this entry.

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