9WNA

[M322I] Menin complexed with DSP-5336

Summary for 9WNA

• Entry DOI: 10.2210/pdb9wna/pdb
• Descriptor: Menin, 5-fluoro-2-[(4-{7-[(1S,3S,4R)-5-methylidene-2-azabicyclo[2.2.2]octane-3-carbonyl]-2,7-diazaspiro[3.5]nonan-2-yl}pyrimidin-5-yl)oxy]-N,N-di(propan-2-yl)benzamide, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: human menin, transcription, m322i mutant inhibitor complex, ds1594
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 110888.38

Authors

Bijpuria, S.,Mckeever, B.M.,Mcgeehan, G.M. (deposition date: 2025-09-04, release date: 2026-04-29, Last modification date: 2026-05-13)

• Primary citation: Bijpuria, S.,Mckeever, B.M.,Mcgeehan, G.M.; [M322I] Menin complexed with DSP-5336; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)