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9WN5

Human Pin1 (Peptidyl-prolyl cis-trans isomerase) catalytic domain in complex with a covalent inhibitor

This is a non-PDB format compatible entry.
Summary for 9WN5
Entry DOI10.2210/pdb9wn5/pdb
DescriptorPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ~{N}-[(3~{R})-1,1-bis(oxidanylidene)thiolan-3-yl]-~{N}-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]ethanamide, 3-[bis(oxidanyl)methyl]pentane-1,1,3,5,5-pentol, ... (4 entities in total)
Functional Keywordshuman pin1, peptidyl-prolyl cis-trans isomerase, covalent inhibitor, isomerase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight27738.87
Authors
Wang, X.Y.,Zhang, D.P.,Zhou, J.,Xu, B.L. (deposition date: 2025-09-04, release date: 2026-09-09)
Primary citationWang, X.Y.,Zhang, D.P.,Zhou, J.,Xu, B.L.
Human Pin1 (Peptidyl-prolyl cis-trans isomerase) catalytic domain in complex with a covalent inhibitor
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.47 Å)
Structure validation
No wwPDB Validation report is currently available for this entry.

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