9WJ0

Cryo-EM structure of ClassIII Lanthipeptide modification enzyme TherKC with chain A bounded to substrate TherA and ATPrS.

Summary for 9WJ0

Entry DOI	10.2210/pdb9wj0/pdb
EMDB information	66012
Descriptor	Lantibiotic, Protein kinase domain-containing protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total)
Functional Keywords	lanthipeptide modification enzyme, peptide binding protein
Biological source	Thermoactinomyces sp. DSM 45892 More
Total number of polymer chains	3
Total formula weight	204097.24
Authors	Zhang, H.,Luo, M. (deposition date: 2025-08-30, release date: 2026-09-02)
Primary citation	Zhang, H.,Luo, M. Structural Basis for the lanthipeptide biosynthesis mechanism of a dimeric Class III lanthipeptide synthetase To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.35 Å)

Structure validation