9WIQ

Crystal structure of ADC-227 in the avibactam complex (50 mM for 4 hour)

Summary for 9WIQ

Entry DOI	10.2210/pdb9wiq/pdb
Descriptor	Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total)
Functional Keywords	bete-lacatmase, hydrolase
Biological source	Acinetobacter baumannii
Total number of polymer chains	1
Total formula weight	41299.03
Authors	Kawai, A.,Doi, Y. (deposition date: 2025-08-29, release date: 2026-03-25)
Primary citation	Kawai, A.,Doi, Y. Stable cefiderocol resistance mediated by a valine substitution at position 293 combined with an alanine duplication in the omega loop of ADC beta-lactamase in Acinetobacter baumannii Mbio, 2026 Cited by DOI: 10.1128/mbio.03518-25 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation