9WIP

Crystal structure of ADC-227 in the free form

Summary for 9WIP

• Entry DOI: 10.2210/pdb9wip/pdb
• Descriptor: Beta-lactamase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
• Functional Keywords: bete-lacatmase, hydrolase
• Biological source: Acinetobacter baumannii
• Total number of polymer chains: 1
• Total formula weight: 41270.08

Authors

Kawai, A.,Doi, Y. (deposition date: 2025-08-29, release date: 2026-03-25)

• Primary citation: Kawai, A.,Doi, Y.; Stable cefiderocol resistance mediated by a valine substitution at position 293 combined with an alanine duplication in the omega loop of ADC beta-lactamase in Acinetobacter baumannii; Mbio, 2026; DOI: 10.1128/mbio.03518-25

Experimental method

X-RAY DIFFRACTION (1.95 Å)