9WFT

Crystal structure of A0PKV-1 TCR in complex with HLA-A*11:01 bound to G12V-9 peptide(VVGAVGVGK)

Summary for 9WFT

• Entry DOI: 10.2210/pdb9wft/pdb
• Descriptor: HLA class I histocompatibility antigen, A alpha chain, Beta-2-microglobulin, G12V9, ... (6 entities in total)
• Functional Keywords: pmhc, tcr, complex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 97177.40

Authors

Jin, X.Y.,Zhang, Z.Y.,Xi, Y.H.,Gu, Y.H.,Qi, J.X.,Chai, Y.,Tan, S.G.,Gao, G.F. (deposition date: 2025-08-22, release date: 2026-08-26)

• Primary citation: Jin, X.Y.,Wang, W.L.,Zhang, Z.Y.,Gu, Y.H.,Xi, Y.H.,Jiang, M.,Peng, Y.Q.,Yao, P.J.,Tang, L.F.,Ma, K.K.,Wang, J.,Li, F.Y.,Li, X.W.,Jin, W.J.,Chen, Y.,Chai, Y.,Qi, J.X.,Zhang, C.W.H.,Liu, K.F.,Wang, J.,Gao, G.F.,Tan, S.G.; Commensal Clostridium spp. harbor mimetic CTL-epitopes eliciting T cells cross-recognizing KRAS-G12V tumor neoantigen; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.09 Å)