9WF1

PLP and 1-Boc-2-methyl-piperidin-5-one complex structure of an (R)-selective omega-transaminase from Ancylobacter lacus

This is a non-PDB format compatible entry.

Summary for 9WF1

• Entry DOI: 10.2210/pdb9wf1/pdb
• Descriptor: Omega-Transaminase, ~{tert}-butyl (2~{S})-2-methyl-5-oxidanylidene-piperidine-1-carboxylate (3 entities in total)
• Functional Keywords: (r)-selective omega-transaminase, complex with plp and 1-boc-2-methyl-piperidin-5-one, transferase
• Biological source: Ancylobacter lacus
• Total number of polymer chains: 4
• Total formula weight: 144468.86

Authors

Lin, S.,Zhang, Y. (deposition date: 2025-08-20, release date: 2026-02-04)

• Primary citation: Zhang, Y.,Wang, X.,Yin, X.,Huang, T.,Lin, S.; Engineered omega-Transaminase Enables Remote Stereocontrol in the Synthesis of Chiral Pharmaceutical N-Heterocyclic Amines with Nonadjacent Stereocenters; Acs Catalysis, 16:587-598, 2026; DOI: 10.1021/acscatal.5c07044

Experimental method

X-RAY DIFFRACTION (1.93 Å)