9WEF

Plasmodium vivax aspartyl-tRNA synthetase in complex with AMS and SO4

Summary for 9WEF

• Entry DOI: 10.2210/pdb9wef/pdb
• Descriptor: aspartate--tRNA ligase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE, SULFATE ION, ... (7 entities in total)
• Functional Keywords: aminoacylation, aminoacyl-trna synthetase, trna-binding, atp-binding, malaria, inhibitor, ligase
• Biological source: Plasmodium vivax (malaria parasite P. vivax)
• Total number of polymer chains: 2
• Total formula weight: 125735.82

Authors

Manickam, Y.,Sharma, V.K.,Sharma, A. (deposition date: 2025-08-19, release date: 2026-09-02)

• Primary citation: Sharma, V.K.,Manickam, Y.,Sharma, A.; The active site of aspartyl-tRNA synthetase: Structural studies of the adenylation reaction and flexibility of residues.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.402 Å)