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9WE2

Crystal structure of HLA-A*11:01 bound to A0PXA8-V2 peptide(IVGAVGIAK)

Summary for 9WE2
Entry DOI10.2210/pdb9we2/pdb
DescriptorHLA class I histocompatibility antigen, A alpha chain, Beta-2-microglobulin, A0PXA8-V2, ... (4 entities in total)
Functional Keywordspmhc, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains6
Total formula weight89387.27
Authors
Jin, X.Y.,Zhang, Z.Y.,Xi, Y.H.,Gu, Y.H.,Qi, J.X.,Chai, Y.,Tan, S.G.,Gao, G.F. (deposition date: 2025-08-19, release date: 2026-08-26)
Primary citationJin, X.Y.,Wang, W.L.,Zhang, Z.Y.,Gu, Y.H.,Xi, Y.H.,Jiang, M.,Peng, Y.Q.,Yao, P.J.,Tang, L.F.,Ma, K.K.,Wang, J.,Li, F.Y.,Li, X.W.,Jin, W.J.,Chen, Y.,Chai, Y.,Qi, J.X.,Zhang, C.W.H.,Liu, K.F.,Wang, J.,Gao, G.F.,Tan, S.G.
Commensal Clostridium spp. harbor mimetic CTL-epitopes eliciting T cells cross-recognizing KRAS-G12V tumor neoantigen
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.19 Å)
Structure validation

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