9W97

Structure of BPDBA-bound state of the human betaine/GABA transporter 1

This is a non-PDB format compatible entry.

Summary for 9W97

• Entry DOI: 10.2210/pdb9w97/pdb
• EMDB information: 65765
• Descriptor: GFP,Maltose/maltodextrin-binding periplasmic protein,Sodium- and chloride-dependent betaine transporter, 2,4-bis(chloranyl)-~{N}-[1-(phenylmethyl)piperidin-4-yl]benzamide, CHLORIDE ION (3 entities in total)
• Functional Keywords: transport protein, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 1
• Total formula weight: 144818.44

Authors

Wu, J.X.,Zhou, J. (deposition date: 2025-08-09, release date: 2026-05-27)

• Primary citation: Zhou, J.,Liu, J.,Jin, Y.,Wang, Q.,Yu, H.,Wu, J.X.; Substrate recognition and allosteric inhibition of human betaine/GABA transporter 1; Nat Commun, 2026; DOI: 10.1038/s41467-026-72924-5

Experimental method

ELECTRON MICROSCOPY (2.84 Å)