9W0L

S1P3 in complex with CYM52581 and spm242

This is a non-PDB format compatible entry.

Summary for 9W0L

• Entry DOI: 10.2210/pdb9w0l/pdb
• Descriptor: Sphingosine 1-phosphate receptor 3,Endo-1,4-beta-xylanase, [(2~{R})-2-azanyl-4-[2-chloranyl-4-(3-hydroxyphenyl)sulfanyl-phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate, ~{N}-[(~{R})-(5-bromanylpyridin-2-yl)-(3,4-dichlorophenyl)methyl]-4-cyano-3-fluoranyl-benzamide (3 entities in total)
• Functional Keywords: s1p3, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 55268.68

Authors

Beili, W.,Qiang, Z.,Qiuxiang, T. (deposition date: 2025-07-24, release date: 2026-06-03)

• Primary citation: Wu, Y.,Chen, Q.,Wang, H.,Liu, K.,Wei, J.,Wang, M.,Chen, K.,Zhu, Y.,Han, S.,Yi, C.,Ma, L.,Schnapp, G.,Pautsch, A.,Gnamm, C.,Grauert, M.,Schmidt, E.,Tan, Q.,Wu, B.,Zhao, Q.; Structural basis of allosteric and bitopic ligands binding in sphingosine-1-phosphate receptors 2 and 3.; Protein Cell, 2025; PubMed: 40851516; DOI: 10.1093/procel/pwaf068

Experimental method

X-RAY DIFFRACTION (3.6 Å)