9VXM

Human mitoribosome in a non-rotated state, with multiple neomycin molecules bound, featuring A/A-site and P/P-site tRNAs

Summary for 9VXM

Entry DOI	10.2210/pdb9vxm/pdb
EMDB information	65433
Descriptor	Large ribosomal subunit protein bL32m, Large ribosomal subunit protein mL41, 16S mitochondrial rRNA, ... (98 entities in total)
Functional Keywords	mitoribosome, neomycin, ribosome
Biological source	Homo sapiens (human) More
Total number of polymer chains	86
Total formula weight	2953057.61
Authors	Zhu, L.,Jia, C.,Wu, M.,Li, W. (deposition date: 2025-07-19, release date: 2026-07-22, Last modification date: 2026-08-12)
Primary citation	Zhang, X.,Zhu, L.,Jia, C.,Wu, K.,Bai, Y.,Sun, S.,Zhang, Z.,Guo, L.,Hou, X.,Wu, M.,Amunts, A.,Li, W. Human ribosome interactions reframe neomycin toxicity To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation