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9VXM

Human mitoribosome in a non-rotated state, with multiple neomycin molecules bound, featuring A/A-site and P/P-site tRNAs

This is a non-PDB format compatible entry.
Summary for 9VXM
Entry DOI10.2210/pdb9vxm/pdb
EMDB information65433
DescriptorLarge ribosomal subunit protein bL32m, Large ribosomal subunit protein mL41, 16S mitochondrial rRNA, ... (98 entities in total)
Functional Keywordsmitoribosome, neomycin, ribosome
Biological sourceHomo sapiens (human)
More
Total number of polymer chains86
Total formula weight2953057.61
Authors
Zhu, L.,Jia, C.,Wu, M.,Li, W. (deposition date: 2025-07-19, release date: 2026-07-22)
Primary citationZhang, X.,Zhu, L.,Jia, C.,Wu, K.,Bai, Y.,Sun, S.,Zhang, Z.,Guo, L.,Hou, X.,Wu, M.,Amunts, A.,Li, W.
Human ribosome interactions reframe neomycin toxicity
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.9 Å)
Structure validation

257179

PDB entries from 2026-07-29

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