9VX1

The cryo-EM structure of gRNA-bound SPARDA complex

Summary for 9VX1

• Entry DOI: 10.2210/pdb9vx1/pdb
• EMDB information: 65405
• Descriptor: pAgo, DREN-APAZ, RNA (5'-R(P*AP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*CP*UP*GP*AP*CP*GP*AP*UP*A)-3'), ... (4 entities in total)
• Functional Keywords: cryo-em, pago, dren-apaz, cell invasion
• Biological source: Novosphingopyxis baekryungensis; More
• Total number of polymer chains: 6
• Total formula weight: 222655.28

Authors

Li, Y.,Jiang, Y.,Zheng, Q.,Li, S. (deposition date: 2025-07-18, release date: 2026-01-14)

• Primary citation: Li, Y.,Zheng, Q.,Jiang, Y.,Li, S.; Filament assembly induced by the recognition of target DNA activates the prokaryotic Argonaute SPARDA system; Nat Commun, 2026; DOI: 10.1038/s41467-025-68195-1

Experimental method

ELECTRON MICROSCOPY (2.77 Å)