9VWW

Crystal structure of AetF-V220I/S523A in complex with FAD and L-tryptophan

Summary for 9VWW

Entry DOI	10.2210/pdb9vww/pdb
Descriptor	AetF, FLAVIN-ADENINE DINUCLEOTIDE, TRYPTOPHAN, ... (4 entities in total)
Functional Keywords	halogenase, flavin-dependent, single-component, l-tryptophan, flavoprotein
Biological source	Aetokthonos hydrillicola Thurmond2011
Total number of polymer chains	1
Total formula weight	78846.42
Authors	Li, H.,Huang, J.-W.,Dai, L.,Chen, C.-C.,Guo, R.-T. (deposition date: 2025-07-17, release date: 2025-12-10, Last modification date: 2025-12-17)
Primary citation	Li, H.,Huang, J.W.,Dai, S.,Feng, D.,Liu, J.,Zhang, N.,Guo, Y.,Chen, C.C.,Guo, R.T. Enabling Regiospecific Di-halogenation in One-Pot Reactions Using an Engineered Single-Component Flavin-Dependent Tryptophan Halogenase Acs Catalysis, :20879-20888, 2025 Cited by DOI: 10.1021/acscatal.5c06868 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation