9VNY

Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with CYM5442

This is a non-PDB format compatible entry.

Summary for 9VNY

• Entry DOI: 10.2210/pdb9vny/pdb
• EMDB information: 65218
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (6 entities in total)
• Functional Keywords: gpcr, s1pr1, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 174744.34

Authors

Yu, L.Y.,Jiao, H.Z.,Ti, R.J.,Pang, B.,Gan, B.,Ren, R.B. (deposition date: 2025-07-01, release date: 2026-01-28)

• Primary citation: Yu, L.Y.,Jiao, H.Z.,Ti, R.J.,Pang, B.,Gan, B.,Ren, R.B.; Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with CYM5442; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.69 Å)