9VMG

Cryo-EM structure of the spermine-bound sea lamprey TAAR348-Gs complex

Summary for 9VMG

Entry DOI	10.2210/pdb9vmg/pdb
EMDB information	65187
Descriptor	Trace amine-associated receptor 12707.TAAR348, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
Functional Keywords	gpcr, taar348, spermine, sea lamprey, membrane protein/immune system, membrane protein-immune system complex
Biological source	Petromyzon marinus (sea lamprey) More
Total number of polymer chains	6
Total formula weight	155918.81
Authors	Jiang, K.X.,Zheng, Y.,Xu, F. (deposition date: 2025-06-27, release date: 2026-05-13)
Primary citation	Jiang, K.,Zeng, L.,Zhang, W.,He, X.,Zheng, Y.,Wang, L.,Zhang, Z.,Pu, J.,Deng, C.,Yang, F.,Zhao, S.,Xu, F. Chemosensation of the pheromone spermine by the olfactory TAAR-like receptor TAAR348. Cell Discov, 11:79-79, 2025 Cited by PubMed: 41015618 DOI: 10.1038/s41421-025-00839-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.82 Å)

Structure validation