9VJK

Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody 10E6 against Sulfonamides

Summary for 9VJK

Entry DOI	10.2210/pdb9vjk/pdb
Descriptor	Heavy Chain of Antigen-Binding Fragment of Monoclonal Antibody of 10E6, Light Chain of Antigen-Binding Fragment of Monoclonal Antibody of 10E6 (3 entities in total)
Functional Keywords	monoclonal antibody, antigen-binding fragment, sulfonamides, immune system
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	47784.19
Authors	Zhang, Y.,Li, C.,Shen, J.,Wang, Z. (deposition date: 2025-06-20, release date: 2026-06-24)
Primary citation	Zhang, Y.,Li, C.,Zhang, X.,Duan, C.,Shen, Q.,Wu, W.,Yu, X.,Wen, K.,Shen, J.,Wang, Z. Mitigating the Affinity/Specificity Trade-Off: Production of Monoclonal Antibodies with High Affinity and Fine Specificity to Sulfonamides by Ligand- and Receptor-Based Rational Hapten Design Engineering (Beijing), 2026 Cited by DOI: 10.1016/j.eng.2026.02.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.51 Å)

Structure validation