9VIN

Ternary complex of TNFR1-DD, TRADD-DD and RIPK1-DD

Summary for 9VIN

• Entry DOI: 10.2210/pdb9vin/pdb
• EMDB information: 65094
• Descriptor: Tumor necrosis factor receptor type 1-associated DEATH domain protein, Receptor-interacting serine/threonine-protein kinase 1, Tumor necrosis factor receptor superfamily member 1A, membrane form (3 entities in total)
• Functional Keywords: tnfr1, ripk1, tradd, death domain, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 31
• Total formula weight: 411677.07

Authors

Liu, J.,Han, Y.,Zhao, J.,Gao, J.,Yuan, J. (deposition date: 2025-06-18, release date: 2026-04-08)

• Primary citation: Zhao, K.,Liu, J.P.,Liu, C.,Yuan, J.Y.; Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome; Nature, 2026; DOI: 10.1038/s41586-026-10304-1

Experimental method

ELECTRON MICROSCOPY (3.41 Å)