9VF3

Spirooxindole inhibitor CG-1062 complexed with SARS-Cov-2 3CL protease

This is a non-PDB format compatible entry.

Summary for 9VF3

• Entry DOI: 10.2210/pdb9vf3/pdb
• Descriptor: 3C-like proteinase nsp5, (2'~{S},3~{R})-1'-[(2~{S})-2-(2-cyclopropyl-4-oxidanylidene-3~{H}-imidazo[4,5-c]pyridin-5-yl)-4-methyl-pentanoyl]-2'-(iminomethyl)spiro[1~{H}-indole-3,4'-pyrrolidine]-2-one (3 entities in total)
• Functional Keywords: protease, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 35222.13

Authors

Tang, X.,Chen, X.,Hou, K.,Fan, W. (deposition date: 2025-06-10, release date: 2026-06-17)

• Primary citation: Tang, X.,Chen, X.,Hou, K.,Fan, W.; Spirooxindole inhibitor CG-1062 complexed with SARS-Cov-2 3CL protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.964 Å)