9VF2

Spirooxindole inhibitor CG-1059 complexed with SARS-Cov-2 3CL protease

This is a non-PDB format compatible entry.

Summary for 9VF2

• Entry DOI: 10.2210/pdb9vf2/pdb
• Descriptor: 3C-like proteinase nsp5, (2~{S})-~{N}-[(2~{S})-1-[(2'~{S},3~{R})-2'-(iminomethyl)-2-oxidanylidene-spiro[1~{H}-indole-3,4'-pyrrolidine]-1'-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-2-[2,2,2-tris(fluoranyl)ethanoylamino]propanamide (3 entities in total)
• Functional Keywords: protease, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 35245.08

Authors

Tang, X.,Chen, X.,Hou, K.,Fan, W. (deposition date: 2025-06-10, release date: 2026-06-17)

• Primary citation: Tang, X.,Chen, X.,Hou, K.,Fan, W.; Spirooxindole inhibitor CG-1059 complexed with SARS-Cov-2 3CL protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)