9VBQ

Crystal structure of FXR in complex with agonist XJ02862-S2

This is a non-PDB format compatible entry.

Summary for 9VBQ

• Entry DOI: 10.2210/pdb9vbq/pdb
• Descriptor: Bile acid receptor, Nuclear receptor coactivator 1, (3~{a}~{R},7~{a}~{S})-2-[(2~{R})-1-[(2~{R},4~{R})-2-methyl-4-phenylazanyl-3,4-dihydro-2~{H}-quinolin-1-yl]-1-oxidanylidene-propan-2-yl]-3~{a},4,5,6,7,7~{a}-hexahydroisoindole-1,3-dione, ... (5 entities in total)
• Functional Keywords: fxr, agonist., transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 30322.74

Authors

Lu, X.,Zhang, H. (deposition date: 2025-06-04, release date: 2026-06-10)

• Primary citation: Lu, X.,Zhang, H.; Crystal structure of FXR in complex with agonist XJ02862-S2; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.303 Å)